Normal-Tension Glaucoma and Low Cerebrospinal Fluid Pressure

Cerebrospinal Fluid Pressure and Glaucoma

Eyes with normal-pressure glaucoma and those with high-pressure glaucoma can show a similar optic nerve head appearance, while eyes with vascular optic neuropathies show a markedly different optic disc appearance. Factors in addition to intraocular pressure (IOP) may thus play a role in the pathogenesis of glaucomatous optic neuropathy. Clinical and experimental studies showed that (1) physiolo...

Systemic blood pressure in open-angle glaucoma, low tension glaucoma, and the normal eye.

Cerebrospinal fluid exchange in the optic nerve in normal-tension glaucoma.

AIM To report on the cerebrospinal fluid (CSF) exchange between the intracranial spaces (ie, basal cisterns) and the subarachnoid space (SAS) of the optic nerve (ON) in subjects with normal-tension glaucoma (NTG) compared with control subjects without NTG or other forms of glaucoma. METHODS CT cisternography of the brain and orbits was performed in 18 patients with NTG (7 women, 11 men; mean ...

The Optic Canal: A Bottleneck for Cerebrospinal Fluid Dynamics in Normal-Tension Glaucoma?

PURPOSE To report on the optic canal cross-sectional area (OCA) in Caucasian patients with normal-tension glaucoma (NTG) compared with Caucasian control subjects without known optic nerve (ON) diseases. METHODS Retrospective analysis of computed tomographic images of the cranium and orbits in 56 NTG patients (30 females and 26 males; 99 of 112 eyes; mean age 67.7 ± 11.1 years). Fifty-six age-...

Intraocular pressure and central visual field of normal tension glaucoma.

AIM To study whether damage in the central 30 degrees field of normal tension glaucoma (NTG) is relatively heterogeneous or homogeneous with respect to intraocular pressure (IOP) related damage. METHODS Using the results of Humphrey perimeter examinations, the central 30 degrees field was divided into four subfields; superior and inferior hemifields excluding the caecocentral field (30-2 prog...